Zebra ZD421 Barcode Printer, Desktop, Thermal Transfer, 300 dpi, USB, USB Host, Bluetooth LE, RTC

The Zebra ZD421C Printer Series is a compact, desktop thermal transfer label printer family engineered for demanding business and healthcare labeling tasks. Designed for bedside, laboratory, pharmacy, retail and light industrial environments, the series delivers reliable barcode and identification printing with easy ribbon cartridge loading, healthcare-ready materials and multiple connectivity options. Available across variants with 203 dpi and 300 dpi resolutions and print speeds up to 6 inches per second, the ZD421C line balances clarity, throughput and hygienic design to support specimen labels, wristbands, medication tags, shipping and asset labels while simplifying deployment and daily operation in shared or clinical workflows.

Key Features

• Healthcare-ready design: Disinfectant-compatible plastics, sealed buttons and medical-grade power options support hygienic use in clinical settings.
• Cartridge ribbon system: Instant, one-way ribbon cartridge loading with a smart chip for monitored ribbon replacement reduces downtime and simplifies service.
• Flexible print performance: Multiple SKUs offer 203 dpi and 300 dpi resolutions and print speeds up to 6 ips to match needs for durability or high-detail output.
• Broad connectivity: Integrated USB, USB Host, Ethernet and wireless options (Bluetooth, BTLE, Wi‑Fi 802.11ac/802.11ax class variants) enable easy integration into varied IT environments.
• Compact desktop form factor: 4‑inch class footprint with OpenACCESS media loading and multi-sensor support fits crowded workstations and bedside stations.

Specifications

• Brand: Zebra
• Product Family: ZD421
• Product Name: Zebra ZD421C Printer Series
• Product Type: Barcode printer
• Printer Type: Desktop
• Print Method: Thermal Transfer (selected SKUs also support Direct Thermal)
• Print Resolution: 203 dpi; 300 dpi (depending on SKU)
• Maximum Print Speed: Up to 6 ips (varies by SKU)
• Print Width: 4.00 in / 4.09 in (model dependent)
• Maximum Media Width: 4.0–4.9 in
• Connectivity: USB, USB Host, Ethernet, Bluetooth / Bluetooth Low Energy (BTLE), Wi‑Fi (802.11ac/802.11ax class on select SKUs)
• Memory: Flash 512 MB (typical); SDRAM 256 MB (on some SKUs)
• Features / Includes: Ribbon cartridge, OpenACCESS media loading
• Ribbon Smart Chip: Yes (on cartridge-enabled SKUs)
• Modular Connectivity Slot: Yes (select SKUs)
• Durability / Use Case: Healthcare-ready / commercial
• Dimensions: Typical example 10.00 x 8.0 x 7.0 in (SKU dependent)
• Weight: Varies by configuration (examples range from ~5.0 lb to 9.2 lb)
• Printer Language: EZPL